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Exact(37)
Randomization and the double-blind technique are generally considered to be the cornerstones of quality trials.
The Authors highlighted also the weak support by high quality trials (Smith et al. 2012).
We performed a sensitivity analysis on various other meaningful trial subsets of all high quality trials.
One would have thought that the researchers would then compare these "high quality" trials.
Instead, Shang's group chose to only evaluate a much smaller subset of these high quality trials.
Shang and his team deemed that "high quality trials" must fit certain criteria.
Similar(23)
The evidence is not consistent, but a trend does develop if we focus on the better-quality trials.
So, rather than look at individual trials, supporters and critics of acupuncture alike argue that the best evidence comes from pooling data from good-quality trials.
Exclusion of low-quality trials may thus directly impact our clinical practise.
Recent large high-quality trials have questioned the clinical effectiveness of medical expulsive therapy using tamsulosin for ureteral stones.
Clazosentan, magnesium, and simvastatin have been tested in large high-quality trials but failed to show a beneficial effect.
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