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EP conducted the statistical analyses for the quality scoring process.
Any disagreement during the quality scoring process was resolved by discussion with a third author (IJZ).
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Future research should focus on the relationship between order set quality scores and process and outcome measures of quality.
According to our respondents, these are mechanisms by which the portal improves quality scores (HEDIS), clinical process measures, and use of preventive services.
Primary data analysis, the image analysis, base calling and quality scoring of the run, was processed using the manufacturer's software Real Time Analysis (RTA 1.13.48) and followed by generation of FASTQ sequence files by CASAVA.
DNA sequence ladders were processed for quality scoring using a software package based on the poly-phred system [ 23].
Thus, our scoring process ultimately measured the quality of the report of the RCT manuscript, rather than the true methodological quality of the trial as it was conducted.
All studies included in our methodological scoring process have low-moderate quality as presenting in Table 2.
Each fasta and quality score file are processed by choplqb.py with options −w 8 −t 15 for initial data cleaning.
The image analysis, base calling and quality score calibration were processed using the Illumina Pipeline Software v1.4.1 according to the manufacturer's instructions.
The image analysis, base calling and quality score calibration were processed using Illumina Pipeline Software v1.5, and FASTQ reads files containing the sequencing read, quality scores and paired reads information were exported for the following trimming and assembly process.
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