With an ageing global population, the prevalence and burden of RMDs in developing and developed countries 1 is predicted to increase, resulting in reduced quality of life and loss of work productivity, while placing a major burden on national healthcare systems [ 8, 7].
The disease strikes predominantly men between the ages of 20 and 40 years, in their peak productive years, leading to significant loss of work productivity and decreased quality of life.
In this study, we observed significant differences in functional disability, health-related quality of life, fatigue, and work productivity between different levels of disease activity, showing an increase of functional impairment and fatigue and a decrease of work productivity and health-related quality of life with worsening disease-activity states.
OA is the most common cause of mobility loss, severely affects quality of life, work productivity, and cost of health care, and is the most prevalent form of musculoskeletal disease worldwide [ 3– 5].
17 Hypoglycemia, another side effect of many diabetes medications, has the potential to affect many aspects of patients' lives such as quality of life, work productivity, and medication adherence.
Health outcomes of interest (i.e., health-related quality of life, work productivity, activity impairment, and healthcare resource use), were also similar between the two regions.
It is also important to be familiar with the effects that acute cough has on patients' quality of life, work productivity, and the healthcare system; proper awareness of these effects may contribute to better understanding of the social impact of cough.
14 The results presented here reveal that CZP addition to non-biologic DMARDs in patients with long-standing, mostly MDA is associated with increased remission and LDA rates, prevention of worsening and improvements in physical function, quality of life, work productivity and daily activities.
Despite the above limitations, the data show that presence of OA pain has a profound impact on quality of life, work productivity, and healthcare resource use among workers.
The aim of the current study was to quantify the burden of peripheral arterial disease (PAD) with respect to health-related quality of life, work productivity and activity impairment, and healthcare resource utilization.
