Chondrocyte viability is thought to be an important determinant of the quality of repair.
In other words, as the quality of repaired cartilage increased, the VAS and AOFAS scores increased significantly in both groups.
Short-term analysis of the quality of repair, including absence of preoperative symptoms, patient satisfaction, and cosmetic appearance are encouraging.
When using repair materials, chloride penetration is significantly reduced and the residual service life increases depending on quality of repair materials and the variation of cover depth.
Nevertheless, the rational process for selecting optimal repair materials will be needed in order to save the cost and to assure the quality of repair work.
To investigate the ability of delayed gadolinium-enhanced magnetic resonance (MR) imaging of cartilage (dGEMRIC) and T2 mapping to evaluate the quality of repair tissue after microfracture.
An in-vivo study by Power et al. [12] demonstrated that the addition of recombinant human FGF18 (rhFGF18) to microfracture defects in sheep resulted in improved fill and quality of repair tissue with characteristics of hyaline cartilage.
The purpose of this study was to observe the healing velocity and quality of repairing canine radius segmental defect using transferred autologous periosteum combined with fascia lata, which can provide better biological safety than other materials.
This article surveys the current challenges associated with trying to regenerate complex tissues utilizing drug delivery and gives perspectives on the development of translational tissue engineering therapies which promote spatiotemporal cell-signaling cascades to maximize the rate and quality of repair.
Watanabe et al 46 demonstrated the ability of dGEMRIC to evaluate the quality of repair tissue after microfracture.
