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gF appeared to be characterized by genes affecting the quantity and quality of neurons and therefore neuronal efficiency, whereas long-term depression (LTD) seemed to underlie gC.
This provides a mechanism how the right number and probably also the right quality of neurons are chosen to innervate given target tissues.
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The quality of neuron reconstructions and the selected parameters might influence the performance of NeuronStitcher.
Hence, their performance is sensitive to the quality of neuron reconstruction (Supplement, Section 4).
In addition, the quality of neuron morphologies produced by existing efforts, such as those stored in NeuroMorpho.org, varies widely, reflecting the different protocols used in the experiments and reconstruction.
They can't be read off the physical qualities of neurons in the way that the function of DNA is made possible by its physical structure.
How should quality control of neurons be performed?
The fact that Flower fitness fingerprints can provide information about the 'quality of neurons' is exciting and opens the door to explore Flower functions in neurobiology.
The quality of single-neuron recordings was checked throughout the experiments in order to keep the signal-to-noise ratio and the physiological conditions as stable as possible.
For gF, functions which related to quantity, quality or morphology of neurons and synapses still predominated.
There must therefore be a section in the Discussion where the authors address the caveats that arise because the extent and quality of the sensory neurons firing to the optogenetic stimulus is unknown.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com