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Our current results also suggest the possibility that SRP has an additional quality control role in preventing cytoplasmic expression of membrane proteins when the targeting pathway is blocked.
These data strongly support that ER-anchored E3 containing complexes play a quality control role not only for ER proteins, but also for non-ER proteins that are accessible from the cytosol as suggested previously [51].
Definitive evidence for a quality control role of CHIP was provided when it was shown to selectively ubiquitinate thermally denatured luciferase (and not the native form) when captured by Hsc70 and Hsp90 [ 6, 8, 17].
Although the pioneer round of translation was initially believed only to have a quality control role in orchestrating NMD (nonsense-mediated decay) [ 129, 130], evidence suggests that CBC-bound transcripts can undergo multiple rounds of translation generating functional products [ 131– 131].
Although polyadenylation is a distinctive feature of mRNA, polyadenylation of rRNA has been reported to occur in mammals and several unicellular organisms (Candida albicans, Saccharomyces cerevisiae, Leishmania braziliensis and L. donovani), and it may have a quality control role in rRNA degradation [ 91- 94].
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NIH plays an important quality-control role by periodically examining how each Medical Scientist Training Program (MSTP -designated prograMSTP -designated
"With 10% wrong, you can still lose all trust". Even near accuracy would still mean a massive displacement of workers, pushing the jobs to managerial or quality-control roles or putting a "last mile" human face on interactions.
Before becoming a mailbox mogul, he designed baseball bats for Easton Sports and had quality control and management roles at Mattel.
Thus, PINK1 phosphorylation of both ubiquitin and the Ubl are required for Parkin's function in mitochondrial quality control, but their respective roles remain controversial.
During the production process of rolled steel plates quality control plays an important role.
Quality control plays an important role in the tool design, manufacturing process, experiment, project design, and the on-site procedure, all of which were illustrated in the technology of the underbalanced drilling air injection connector system.
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