Basic quality control functionalities of Plink version 1.07 [ 33] (32) were applied: SNPs with a minor allele frequency of less than 1%, missing in more than 5% of individuals and/or violating Hardy-Weinberg equilibrium (p < 1×10−6) were excluded from the reference panel; individuals missing more than 10% of the genotypes were excluded.
Assay quality control data establish the functionality of the quality control system and demonstrates the reliability of the serological data generated using these assays.
These packages are subject to stringent quality control in terms of functionality and documentation.
Given the high number of possible glycans attached to proteins, manifold functions can be attributed to the carbohydrate moiety: folding, stability, conformation, solubility, quality control, half-life, oligomerization or functionality.
2. What is the role of the age-associated protein deposit in the functionality of protein quality control?
Here, we show that an active response to hypoxia disrupts cellular proteostasis – the coordination of protein synthesis, quality control, and degradation that maintains the functionality of the proteome.
Ultimately, the success of a model library depends on a sufficient set of quality components with complementary functionalities, a framework for quality control, and support of the environmental modelling community.
To ensure the functionality of the BG meter, quality control measures were performed on a daily basis using the GlucoRx approved TaiDoc Control Solution (lot number: WA12K002; expiry date: 11/2014) prior to the test procedure.
Multiprotein complexes (for instance, ion channels and immune receptors but also enzymatic activities such as γ-secretase) require additional secondary quality control that ensures proper assembly of individual subunits and functionality of the complex [ 5, 6].
In terms of functionality, the main differences lie in the quality control and normalization tools.
