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Technological approaches, however, are often designed to use the whole speech signal without taking into account the qualitative variability of the spectral content.
Despite the qualitative variability of stiffness within and adjacent to a given malignancy on a single acquisition, quantitative assessment of maximum and median elasticity were highly reliable across multiple SWE acquisitions.
Such qualitative variability in gene expression is most likely based on genetic background, whereas the resulting pathology derives from the interaction between the genome and epigenome with environmental factors and physiological stress.
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Such qualitative variabilities within the same cell population are generated by epigenetic commitment of cells to different fates (e.g., proliferation versus differentiation) as well as by genetic alterations (Fig. 1b) as in cancer [ 13, 14].
With our small sample size, success rate estimates of qualitative variables have a high variability; statistically significant results or strict dose-response patterns cannot be expected for qualitative parameters such as remission or mucosal healing.
For measurable (quantitative) variables, arithmetic means, standard deviations, medians, as well as the range of variability (extremes) were calculated, while for qualitative variables, the frequency (percentage) was determined.
However, these qualitative measures exhibit variability and must be assessed over long periods of time.
Clearly more qualitative observation of variability will inform item construction choices for quantitative measures.
Given that the qualitative findings suggest variability in the delivery of the BI and use of MI techniques, further research is warranted to evaluate the actual counselling content and quality of patient-centred discussions at each step of the intervention.
The differences in predictability of bias direction and the prevalence of high risk phenotype in normal tissue between the PAM50 and the other predictors can be explained by qualitative differences in variability of each gene set across normal samples.
All experiments were on vermal lobule V, but qualitative observations suggested limited variability among different lobules.
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