Sentence examples for qualitative defect from inspiring English sources

Taken together, these results demonstrate that ectopic HH signaling activity in proximal ureteric cells causes renal hypoplasia, characterized by marked defects in the formation of nephrogenic structures, reduced ureteric branching and a qualitative defect in early stage ureteric branch tips.

The three hereditary types of VWD described are type 1, type 2 and type 3. Type 1 is a quantitative defect and type 2 is a qualitative defect.

Our data therefore suggest that the deficit in IL-7 in RA may contribute to the qualitative defect in Th1 polarization.

We reasoned that the type of Mitotracker used for the staining was also able to detect a qualitative defect in the mitochondrial membrane potential (Δ Ψm) (14).

Hypomineralisation is defined as a qualitative defect of the enamel caused by a disturbance during initial calcification and/or during maturation [ 1, 3].

Prolongation of both PT and APTT can be caused by isolated congenital coagulation factor deficiencies of the common pathway: fibrinogen, FII, FV or FX, or a qualitative defect of fibrinogen (dysfibrinogenemia) (Fig.  1).

Thus, quantitative or qualitative defects of Treg may be observed in human autoimmune diseases.

Thus, male infertility in Ing2−/− mice is attributed to quantitative and qualitative defects in mature spermatozoa.

T-reg cells are present in the peripheral lymphoid organs of NOD mice some 3 days after birth, but the adult NOD mice display quantitative and qualitative defects in the T-reg compartment [7] including the NK cells [50], [51].

These findings do not support the idea that qualitative defects in specific TCA cycle enzymatic pathways account for the switch from OXPHOS to aerobic glycolysis seen in the majority of cancers [20].

As our results are described on a genetic background similar to the one reported by Ruggiu et al [22], (with the addition of the FVB background from the Oct4ΔPE GFP transgenic mice [40]), we suggest that the difference in these results may be due to the our use of FACS to capture and characterize PGCs, thus enabling us to uncover much earlier quantitative and qualitative defects in Dazl null PGCs.