This analysis produced putatively hypermutation negative sequence alignments by removing columns suspected of hypermutation.
To confirm that the method described here performs routinely, we have subsequently chosen three additional wheat genes putatively encoding negative regulators of plant disease resistance and screened our HII mutant population to identify homoeologue deletions in these genes.
Analysis of transcript levels by qRT PCR allowed the expression of these isoforms to be differentiated; our data indicate that both isoforms are involved in the observed MXI1 overexpression in tumours, but that the putatively dominant negative isoform may be involved in the evolution of Barrett's metaplasia.
After Mitt Romney lost the 2012 Presidential election, conservative operatives concluded that they needed their own putatively independent negative-campaign machine.
Our results demonstrate that long term E2-treatment of the putatively ER-negative human breast adenocarcinoma cell line MDA231, causes a substantial elevation in endogenous NO levels by modulating NOS expression.
In this study, we have investigated the effect of long term E2-treatment on the expression of NOS activity in the putatively ER-negative human xenograft MDA231 and propose that NO is an important mediator in promoting this increase in tumour growth rate.
This finding has been taken as evidence of a "negative emotion specific deficit", putatively associated with a dysfunction in the limbic system, particularly the amygdala.
Recent tests for protease activity of glands of the two respective genera were negative [ 93]; however, putatively mutualistic arthropods have been reported to be associated with each genus [ 94], from which the plant might benefit in a manner similar to the symbiosis observed in the African Roridula (Roridulaceae, Ericales) [ 93].
In summary, our screen has uncovered numerous genes and functions putatively involved in the positive and negative regulation of acetic acid-induced PCD.
Thus, it appears that, depending on the strength and amount of negative selection acting on putatively functional windows used to train our SVM and the strength of recent selective sweeps occurring in the human genome, positively selected regions may often be classified as constrained.
