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Summary of putative microRNAs.
Sequences and folding structures of two predicted putative microRNAs.
Putative microRNAs were checked to remove repetitive sequence and transposable elements.
In order to identify putative microRNAs, we screened all RNAz hits with RNAmicro [ 35].
This disparity highlights the utility of miRDeep to identify putative microRNAs that are mostly primate-specific.
Similarly, for given protein coding gene, there are often many putative microRNAs.
Similar(33)
This study evidenced miR-130 a putative microRNA that targets Erk1/2 (Mask1) 3′UTR- as a necessary linkage in the control of Fgf8 signaling, mediated by Bmp2.
Although the cadherin-11 3'UTR contains putative microRNA target sites and is regulated by Dicer, its stability is not regulated by GSK3 inhibition or density.
Gene transcript levels are directly derived from microarray data, while microRNA regulatory effects are modeled using mRNA sequence information, with the assumption that mRNA with similar putative microRNA binding sites are likely to experience similar posttranscriptional regulation.
By examination of the promoter regions of putative microRNA targets, they found that some transcription factor motifs were significantly enriched, E2F-1 (p-value = 6.01×10−14), KROX (p-value = 9.34×10−14), MAZ (p-value = 2.23×10−11) and PAX6 (p-value = 1.76×10−9).
We did not identify any putative microRNA precursors.
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