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Since that time, the mujtahids (i.e., the Shīʿite divines) have been able to interpret law and doctrine under the putative guidance of the imam, who will return toward the end of time to fill the world with truth and justice.
UNC-40/DCC is a good candidate of the putative guidance receptor.
Given the fact that lin-12 is expressed and cell-autonomously required in the postsynaptic target cell vm2, and that the activity of canonical LIN-12/Notch signaling pathway is involved, we speculate that the putative guidance receptors could be the downstream target genes of the canonical LIN-12/Notch pathway.
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Previously, we found that miR-29a whose levels are decreased in the frontal cortex of AD brains targets neuron navigator 3 (NaV3), a putative axonal guidance regulator [ 62].
We agree that additional experimental data could add substantially to this work – in particular, the identification of putative growth and/or guidance molecules that act through Fz3, or putative intermediate target-derived trophic factors.
In the absence of specific antigen, T cells were found to migrate autonomously in the T cell area and B cells likewise in the follicle, apparently providing no evidence for the directional guidance of putative chemokine gradients [ 22, 23].
However, a clinician confronted with a putative S. aureus infection needs guidance.
Besides the "first waiting period" related guidance cues and the putative "handshake" cues, in Brn4 Cre ;Wnt3a DTA mutant mice model, in which TC projections are completely ablated because no specific markers expressing on the pathway are detected, also displays an undoubted misleading phenotype that all the CT neurons go through GP and finally reach CP (Deck et al., 2013).
Our data illustrated that, similar to TNTs between astrocytes, S100A4 and its putative receptor RAGE were essential for TNT guidance toward neurons and between neurons and astrocytes.
However, the putative participation of one of the major families of axon guidance molecules in this process, the Semaphorins, was not explored.
To enable comparability with data from the cLOH approach described above, we also adopted different guidance regarding how we treated homozygous SNPs in these putative LOH regions defined by the traditional approach.
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CEO of Professional Science Editing for Scientists @ prosciediting.com