Sentence examples for putative efficacy from inspiring English sources

With the limitation of an open-label design, these data suggest for the first time the putative efficacy and safety of aripiprazole in combination with a tricyclic medication in drug resistant depressed patients.

These trials have generated opposing data on putative efficacy but no important safety concerns have arisen.

Despite some previous information on other types of carcinomas, sometimes divergent, the putative efficacy on bladder cancer remains to be elucidated and more experimental research is justified.

This could imply that the putative efficacy of metformin in preventing GD could be amplified by an ultimate overestimation of the PCOS diagnosis and, therefore, of the metabolic risk among participants.

These tumors are intrinsically sensitive to DNA damage response inhibitors, such as the PARP inhibitors, whose putative efficacy leverages upon a synthetic lethal effect [ 9] in which cell death results from mutations in two or more genes but not in each gene individually (reviewed in [ 10]).

The omega-3 fatty acids, due to their antioxidant and anti-inflammatory properties have been tested as chemopreventive and/or therapeutic agents, per se and in combination with drugs and/or radiotherapy, in several cancer types [ 27– 30], but the putative efficacy on bladder cancer remains to be elucidated.

The fact that reinstatement after CPP extinction is abolished by RS127445, a selective 5-HT2B receptor antagonist in WT mice highlights the putative clinical efficacy of 5-HT2B receptor blockade in the treatment of MDMA abuse.

Most of the putative evidence for efficacy of the many claimed treatments is anecdotal, subjective or non-existent (Lis-Balchin 1999; Hexsel and Mazzuco 2000; Sainio et al 2000; Sadick and Mulholland 2004; Rotunda et al 2005).

Firstly, our currently used animal models for PD need to be refined in order to more reliably predict the efficacy of putative neuroprotective agents in subsequent clinical studies.

Accordingly, a need exists to enroll recently depressed patients in maintenance studies to elucidate the complete spectrum of efficacy of putative mood stabilizers and improve the long-term treatment of bipolar depression.

This mouse model of EHV-1 infection, first described by Awan et al. in 1990 [22], has been intensively used to predict the efficacy of putative EHV-1 vaccines in horses [23] [26], as well as the virulence potential of several EHV-1 strains [27] [32].