"They enable everyone, young and old alike, to pursue hypotheses that are not heavily driven by preceding work," he says.
The establishment of a genetic complementation system for MVA now allows for genes, other than udg, to be deleted from the viral genome to pursue hypothesis-driven efforts to maximize vector immunogenicity.
May 12 , 2008- Dr. Bernadine Healy, former head of the NIH and the American Red Cross and current Health Editor of US News & World Report tells CBS News that, "Officials have been too quick to dismiss the hypothesis as irrational," and says they "don't want to pursue a hypothesis because that hypothesis could be damaging to the public health community at large by scaring people".
In this paper we pursue the hypothesis that acceptance of the energy transition is not merely determined by technology acceptance but also by the perception of socio-institutional stakeholders and the perception of fairness.
Herein, we pursue the hypothesis that the structure of nordihydroguaiaretic acid (NDGA) can be refined for selective potency against the insulin-like growth factor 1 receptor (IGF-1R) as a potential therapeutic target for breast cancer while diminishing its action against other cellular targets.
To pursue this hypothesis, a time course study of HIF-1 α disappearance in the presence of protein translational inhibitor, cycloheximide (CHX), was performed.
To pursue this hypothesis further, we attempted to correlate both the HRneg/Tneg and IR-7 indices with an assessment of lymphocyte infiltration within the cohort tumors.
We asked this question to pursue the hypothesis that use of phenoxyacetic acid herbicides [2,4-dichlorophenoxyacetic acid (2,4-D), 2,4,5-trichlorophenoxyacetic acid (2,4,5-T)] in the past would be associated with exposure to PCDDs.
In fact, the point estimate suggested that consuming water with total coliform of 5 or more cfu/100 ml was associated with fewer AGII symptoms, however, our sample size was too small to adequately pursue this hypothesis.
Therefore, to further pursue our hypothesis that proton-coupled glucose symport could be conserved in mammals, we then conducted a series of experiments using the mammalian GLUT12 facilitative glucose transporter, of which the closest non-animal relatives were shown to be proton-coupled hexose symporters of Viridiplantae (Additional file 1: Table S1 and Figure S1).
To pursue this hypothesis, we took advantage of available RNASeq data (cfr. M&M) from liver (83 Mb uniquely aligned) and cerebral cortex (105 Mb) of a 60-day post fertilization Belgian Blue fetus shown by SNP genotyping to carry the arthrogryposis risk haplotype.
