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To date, DNA vaccines have been tested in numerous Phase 1 and Phase 2 clinical studies, both for prophylactic and therapeutic purposes (reviewed in refs. 14 and 15).
Alternatively, it has been hypothesised that neurons retract from the cell cycle to use their cell cycle machinery for neuroplastic purposes (reviewed in [ 3]).
The development of RNA interference as a therapeutic tool to silence gene expression has spurred the search for novel and improved pharmaceutical properties for medicinal purposes (reviewed by Rettig and Behlke).
This ability is of special interest for biotechnological purposes (reviewed in [ 62, 63]) and therefore, we incorporated both the msc-PHAs biosynthetic and TOL biodegradative pathways into the metabolic reconstruction (see below).
In crustaceans, melatonin has been shown to have diverse physiological purposes (reviewed in [ 7]): Tilden et al. 2003 [ 8] have demonstrated that melatonin modulates locomotory activity, glucose/lactate levels and neurotransmitter release in crayfish.
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Synteny, the conservation of gene order along the chromosomes of related species, is a genomic property that can be exploited for this purpose (reviewed in [ 1- 3]).
From there, businesses need to consider which SDGs reflect their own purpose, review existing sustainable development work in the bigger picture context of the goals, and identify where they stand to make the most difference, says Cramer.
The use of fibre reinforced composite materials for biomedical purposes is reviewed.
For our purposes, we reviewed mild cognitive impairment when discussing MND.
The benchmark that has been selected for comparison purpose is reviewed extensively.
In this paper, the CHF correlations developed specifically for this purpose are reviewed.
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