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For this purpose, gene expression data generated by a screen that compared normal human prostate specimens with primary prostate tumors [61] were used (two-group t-test (p<0.05)).
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For quality control purposes, gene expression data were filtered based on detection scores defined by Illumina (detection P < 0.01).
One of purpose of this paper is to use gene expression data to show that similar to the example of the marble in the bowl, the gene networks will also have stable and unstable states and that unstable gene networks may be associated with the diseases.
For this purpose, we downloaded gene expression data from a large number of normal human tissues [ 16] and generated 52 gene sets corresponding to 26 tissues.
For comparison purposes, metabolic and gene expression data were collected from human breast tumors belonging to corresponding molecular subgroups.
Our purpose has been to investigate pathways and transcription factors involved in metastasis by use of gene expression data sets.
For this purpose, we used the gene expression data obtained from Affymetrix HG-U133A arrays and performed two-way hierarchical clustering with each of those gene sets using GENEVESTIGATOR [ 30].
For the purpose of novel catalyst discovery, gene expression data can be used to prioritize candidates for further analysis.
For this purpose, we employ time-course gene expression data, extracted at predefined time-intervals during the follow-up period from circulating blood cells.
For this purpose, we compared publicly available gene expression data for high-risk neuroblastomas with recorded MNA and 11q status (see Methods).
A. thaliana, not being a non-model organism, is used as the target genome for experimentation purposes only, so that the gene expression data available for A. thaliana can be used for analysis and verification of the mapped regulatory relationships determined using the proposed method.
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