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The goal of this study is to confirm purported risk factors using a well-designed statistical model.
The field's understanding of CD etiology will benefit from larger, adequately powered studies in gene identification efforts; the incorporation of polygenic approaches in gene-environment interplay studies; attention to the mechanisms of risk from genes to brain to behavior; and the use of genetically informative data to test quasi-causal hypotheses about purported risk factors.
In this general population cohort, associations with previously purported risk factors were evident including psoriasis, heart failure, hypertriglyceridemia, and cyclosporine therapy.
Valproic acid has no significant DDIs with DAAs; however, valproic acid use in HCV has been limited by its purported risk of hepatotoxicity [ 58].
There is increasing media attention and public concern over the purported risk that repeated MTBI can lead to subsequent chronic cognitive impairment (CCI), dementia, or to other distinct neurodegenerative disorders (e.g., chronic traumatic encephelopathy (CTE), Parkinson's disease (PD)).
Thus, individual studies require large sample sizes and/or lengthy follow-up periods to detect statistically and clinically significant differences in the risk of revision associated with purported risk factors.
Similar(54)
Although many studies examine purported risks associated with sexual activities, few examine potential physical and mental health benefits, and even fewer incorporate the scientifically essential differentiation of specific sexual behaviors.
As a psychiatrist, I am upset by the inaccurate claims relating to mental health, including purported increased risk of depression, suicide or other negative outcomes following abortion.
The role for environment in the development of type 1 diabetes has remained elusive, with multiple factors purported to modulate risk for this disease (e.g., viruses, breast-feeding, age for cereal introduction, and childhood immunizations) (1, 2).
The purpose of this study is to assess the relationship between self-reported uveitis and purported demographic and clinical risk factors, using an American adult population extracted from the National Health and Nutrition Examination Survey NHANESS) for the years 2009 and 2010.
Antidepressant (AD) use has been purported to increase the risk of breast and ovarian cancer, although both epidemiological and pre-clinical studies have reported mixed results [1] [6].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com