Thus, the consequence of FHM2 mutations is a loss-of-function mechanism with non-functional proteins impairing pump function.
Immunocytochemistry of the cell sheet revealed a positive staining for Na+-K+ ATPase which is a major functional protein involved in the pump function of the corneal endothelium.
Again, a functional study confirmed that ATP2B3 mutations impair activity and inactivate pump function.
As Wood explained, "If even the healthiest hearts after a marathon leak a heart enzyme or demonstrate reduced pumping function, those with sick hearts will have trouble".
It means the heart stops its usual pumping function; good oxygenated blood should be pumping from the left ventricle, coming back to the right, but suddenly it's not.
Congestive heart failure (also called heart failure) is a condition resulting from a variety of cardiac diseases associated with an inadequate pumping function of the heart.
(B) Disturbance of pumping function by type-2 alkenes.
The pumping function of the LVAD is highly dependent on both preload and afterload.
In a normal pump function, the rollers have moved approximately 60° from their original position.
