Zamoon, J., Nitu, F., Karim, C., Thomas, D. D. & Veglia, G. Mapping the interaction surface of a membrane protein: Unveiling the conformational switch of phospholamban in calcium pump regulation.
In Vibrio cholerae, LTTRs are associated with efflux pump regulation, which contribute to antimicrobial resistance, and are involved in colonization of the human host [ 46].
As SPH-1-P affects ion channels in guard cell protoplasts [ 32], we speculate that this lipid messenger may have a role in water pumping regulation in Utricularia traps, which is associated with potassium channels in trap bifid glands [ 36].
"Drought is the classic crisis and opportunity, and we have been able to use it in that sense". Indeed, the California drought gave Brown the political cover to pass the first groundwater-pumping regulations in state history.
The results of this study also reveal the mechanism of SERCA Ca2+ pump's regulation by PLN.
At the level of Na+/K+ pump down-regulation, survival of normal neuronal cells or even drug-sensitive glioblastoma cells are not affected.
Since the SERCA pumps regulate SR Ca2+ load and, thus, contractility, the SERCA pumps are also crucial for Ca2+ regulation and EC coupling.
In damaged and diseased CE, any acute or accelerated loss of corneal endothelial cells (CEnCs) significant enough to cause a functional imbalance, will result in a leakier CE layer and weakened pump function, hindering regulation of corneal hydration7,8,9.
The indirect contribution of Na+-K+-ATPase pump to pHi regulation in the presence of ethanol (50 mM) was evaluated using its specific inhibitor ouabaïn (1 mM).
3, 4 The hypoperfusion pressure and its consequences might not be manifested in the time following standing, probably because other compensatory mechanisms, such as neurovascular compensation, the skeletal muscle pump, and neurohumoral regulation, are responsible for orthostatic blood redistribution.
Additionally, we designed multiplex PCR protocols for high-throughput sequencing of the QRDRs of topoisomerase genes gyrA, parC and parE, and/or the multidrug efflux pump AcrAB expression regulation systems acrRAB, marRA, and soxSR (with maximum of six PCR products).
