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Conclusion: Because reductions in sodium pump number can result in hormone release from secretory tissues and in contraction of muscle, this suggests that the sodium pump may play a significant role in the initiation or maintenance of human labor.
Thereby, the proton pump may play an important role in the modulation of various physiological functions.
It is possible that drug resistance mediated by different mechanisms co-exists in one strain, but efflux pump may play a more important role [ 26, 27].
The enrichment of antimicrobial peptide transporters and the multidrug efflux pump may play a primary role in the stable colonization of gut microbes in the adult intestine by conferring resistance to CAMPs.
Since the BCAM0925-0927 efflux operon shares considerable homology with latter P. aeruginosa system, the mutant phenotype also suggests that the pump may play a role in chlorhexidine efflux in B. cenocepacia.
To assess the role that this pump may play in salicyl-AMS accumulation levels, we pretreated E. coli with phenylalanine arginine-β-naphthylamide (PAβN, 38 μM, tryptic soy broth) to inhibit AcrAB-TolC, followed by the addition of salicyl-AMS (100 μM).
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Single nucleotide polymorphisms (SNPs) in ABC drug efflux pumps may play a role in responses to drug therapy and disease susceptibility.
To assess the roles that other efflux pumps may play in salicyl-AMS accumulation levels, we pretreated E. coli with carbonyl cyanide m-chlorophenylhydrazone (CCCP, 100 μM) to collapse the proton-motive force (pmf) that energizes most efflux pumps.
Furthermore, it has been suggested that multidrug efflux pumps may play a role in exporting quorum sensing molecules out of the cell as well as flagellar motility which is associated with biofilm formation [ 51].
The possibility of downloading a patient's pump data may play a contributing role to addressing this issue, as it allows the health care professional to follow patient's adherence and to intervene with personalized educational programs.
These results reveal an intimate functional association between CRAC channels and Ca(2+) pumps in the plasma membrane which may play an important role in governing the time course and magnitude of Ca(2+) signals in T cells.
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