Sentence examples for pump impairment from inspiring English sources

Several studies support the hypothesis of cortical excitability as a possible mechanism underlying their pathology, such as Na + −K + ATPase pump impairment, converging on a common final pathway represented by neuronal membrane hyperexcitability, could manifest as either epilepsy or headache/migraine [9].

Since maximal pump impairment by CsA correlated with a concomitant intracellular CypB diminishment (about 5-fold.

The isolation and characterization of a series of new missense alleles of ATPalpha in Drosophila provides the foundation for further studies of these neurological diseases and the role of sodium pump impairment in animal longevity.

Also the duplication of exon 21 of ATP1A2 is expected to alter the function of the alpha(2) subunit of the Na/K pump by the impairment of domain M9, where exon 21 is located.

In contrast, ventricular pacing induces an abnormal electrical activation pattern, which may cause mechanical dyssynchrony, associated with impairment of pump function, LV remodeling, and increased risk of heart failure [ 4– 10].

Known Na+, K+ ATPases alpha disease-causing mutations are dominant and appear to confer a loss-of-function resulting either from haploinsufficiency or a mild hypomorphic impairment in pump function (de Carvalho Aguiar et al. 2004; Pietrobon 2007).

At the same time, LED pumping eradicates the temporal impairment of output pulses which is otherwise unavoidable in case of continuous wave laser pumping.

BCMrch and BCMrun reflect natural hydrologic conditions and do not account for diversions, reservoir storage or releases, urban runoff, groundwater pumping, or other impairments, and therefore will not exactly match measured streamflow in impaired basins.

See Figure 3F) at doses much higher (10 µM) than the ones required for calcineurin inhibition (at the nM range), we reasoned that impairment of the pump relates with the drop of intracellular CypB levels.

In the cardiomyocyte, this alters ion channel flux leading to reductions in pump function and ultimately contractile impairment [ 20].

1 HF is a complex clinical syndrome of symptoms that suggests impairment of the heart as a pump supporting physiological circulation.