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Thus, the consequence of FHM2 mutations is a loss-of-function mechanism with non-functional proteins impairing pump function.
Immunocytochemistry of the cell sheet revealed a positive staining for Na+-K+ ATPase which is a major functional protein involved in the pump function of the corneal endothelium.
Again, a functional study confirmed that ATP2B3 mutations impair activity and inactivate pump function.
In a normal pump function, the rollers have moved approximately 60° from their original position.
Deterioration of calf muscle pump function is associated with progression of chronic venous insufficiency (CVI).
The main physiological functions of this network are to retain tissue integrity and cardiac pump function.
Deformation and wall-thickening of ventricular myocardium are essential for cardiac pump function.
Pseudo-PEA is regarded as a severe form of cardiogenic shock with low or very low pump function.
The pump function of the HCEC sheets thus obtained was approximately 75%95%% of that for human donor corneas.
This scar keeps the heart intact so that the wall of the heart does not rupture, but it is unable to contract or beat, thus weakening the overall pump function of the heart.
As a consequence, the pump function was reduced (see below).
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CEO of Professional Science Editing for Scientists @ prosciediting.com