Sentence examples for pump contributes from inspiring English sources
The P-glycoprotein efflux pump contributes to multi-drug resistance in cancer cells, reducing the efficacy of chemotherapeutic agents [3].
The hepatic ABCC2 [ 30, 31] pump contributes to bile flow and is the main regulator of liver cancer chemoresistance [ 32– 32].
These results suggest that administration of relaxin using an implanted subcutaneous osmotic pump contributes to the increases in systemic relaxin concentration in which β-estradiol and progesterone may act as regulators of systemic relaxin concentration.
A recent study has demonstrated that the positive regulation of the AdeL regulator for the AdeFGH resistance-nodulation-cell division (RND) efflux pump contributes to the multidrug resistance phenotype [ 24]; the AdeABC [ 25] and AdeIJK [ 26] efflux systems have also been demonstrated to contribute to a MDR phenotype.
The discovery, in 1854, that a cholera outbreak in London was caused by a cesspool leaking into a water pump contributed to the development of modern epidemiology and the modern municipal sewer.
In addition, due to the poor overlap between the pump light and a-Si H a-Si H region only activetion of the eneregion the pump conlyibute to modulation.
To clarify the extent to which the AcrAB-TolC pump contributed to organic solvent tolerance in JA300 acrR IS marR, a JA300 acrR IS marR-based acrA-disruptant, JA300ΔacrA acrR IS marR, was constructed and then the organic solvent tolerance of this acrA-disruptant was compared to that of JA300ΔacrA (Figure 3).
This might especially be true where municipal pumping contributes to riverbed clogging.
Consequently, when these pumps are present in the tumor cells concurrently, each of the pumps contributes to the efflux and decrease of intracellular drug concentrations.
A reduction in drug influx via drug solute carriers or increased drug efflux via ATP-binding cassette efflux pumps contributes to a reduction in drug accumulation [ 25].
Moreover, while some genes, such as those that code for drug efflux pumps, contribute to resistance to a wide range of compounds, many others are drug or drug class specific.
