Sentence examples for pulmonary organs from inspiring English sources

A few studies in lung tissues suspected translocation and diffusion of silica nanoparticles away from the lung tissue through systematic circulation and deposition in extra pulmonary organs [196, 197, 198].

However, just a very small fraction of these fine and ultrafine particles accumulate in extra pulmonary organs such as the liver and the spleen, [ 39] and currently there is no final evidence that fine particles physically enter and deposit in blood vessels.

Ultimately, pulmonary organ dysfunction is manifest by hypoxia, hypercapnia and increasing ventilatory pressure.

Previous work has shown an inconsistent relation between a conventional marker of pulmonary organ failure (PaO2/FiO2) and outcome [ 22, 28], mostly due to its dependence on ventilator settings.

Several investigators have described the importance of this process by identifying a correlation between alveolar cytokine levels and the severity of pulmonary organ injury [ 7- 11].

Most recently, Nakasuji and colleagues found that prolonged ICU stay of more than three days was a sensitive and specific measure of adverse outcome that reflected measures of cardiovascular and pulmonary organ failure [ 11].

Another critical, overarching message that needs to be considered before placing a patient on ECMO support is the fact that one of the most significant mortality risks associated with this therapy is the extra pulmonary organ function at the time of initiation of ECMO therapy [ 69].

Although several hospital-based cohort studies have suggested that several factors, including increasing age, sepsis syndrome, and cardiovascular or pulmonary organ failure, increase the risk for developing sARF, these studies potentially suffer from selection bias, and no study to date has been adequately designed to determine actual risk factors in a non-specific general population [ 2, 10- 13].

Experimental ALI downregulates angiogenic gene expression not only in the lung but also in extra-pulmonary organs.

In contrast, alterations in histone lysine acetylation appear more important than alterations in histone methylation in aberrant transcription of angiogenic genes in extra-pulmonary organs.

Thus, ALI-sepsis-induced decreases in H3K4m2 and HK4m3 may account for the greater sepsis-induced repression of Angp1, Tek, and Kdr transcription in the lung compared with extra-pulmonary organs (Fig.  3).