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However, we know it was not published manually.
In these cases, we instead used published, manually curated sequences [ 9] or the appropriate RefSeq entries when those were not available.
Using previously published manually curated functional annotations of the relatively quantified proteins; it becomes apparent that a large part of all proteins detected at higher abundance in heterocysts belong to the adaptive metabolism [ 27].
Until recently this would have limited the use of this approach to organisms with published manually curated metabolic models (for example [ 7]) and organisms that are present in such metabolic network databases as KEGG [ 8] and BioCyc [ 9], many of which are not subject to any curation.
Beside its pathogenic lifestyle and numerous technical advantages of this fungus, the recently published manually annotated proteome, which is available on the public server of the Munich Information Center for Protein Sequences (MIPS; [ 13, 14]) established this fungus as a powerful model system for molecular phytopathology [ 15- 17].
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Here, through screening of published data manually, we collected validated lncRNAs associated regulatory relationships.
Despite using a large number of search terms to identify published studies, manually reviewing all abstracts and relevant reference lists, it is possible we missed some relevant studies.
This massive amount of available literature and its unstructured nature make it virtually impossible for researchers to keep track of all published results manually.
The date stamps of the feeds cluster closely together which indicates that a staff member working for the site publishes them manually rather than being generated automatically when an order is placed.
References cited in the articles of interest and published reviews were manually searched to find any additional reports.
We extracted all human proteins that are related to vitamins; all published information was manually checked to identify its relatedness to vitamins.
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CEO of Professional Science Editing for Scientists @ prosciediting.com