We analyze whether there is a relation between the reliability of published interactions and the popularity of the interaction partners.
This result illustrates that the overlap with high-throughput data is indeed a good indicator for the reliability of published interactions, since interactions that are repeated many times in the literature can be expected to be more reliable.
The co-immunoprecipitation experiments were also consistent with the recently published interaction map of endoplasmic reticulum chaperones and foldases (36).
The modification has required a reestimation of previously published interaction parameters.
In one study published recently interaction of OS-9 with HIF could not be confirmed [52] which is in line with our data.
The biological functions of each of the 13 clusters were analyzed in the context of a curated list of published molecular interactions by IPA.
The results indicate that there is a potentially large number of published drug interactions that are not captured by DrugBank.
Published evidence of interactions from different databases is present in the output HTML files.
None of the Env-receptor inhibitors or published inhibitors of interactions driving phagocytosis of dead/dying cells reproducibly and significantly blocked HIV-1+ T cell uptake.
We estimated that approximately 10% of the published molecular interactions are logically incompatible.
