Experiment reproduction code is published separately, as described in Section 4. The system design of Hidost is illustrated in Fig. 8.
Data related to treatment outcomes were pooled from published studies as described above.
Au nanorods were prepared based on modifications of published protocols, as described previously.
In conducting thematic content-analyses, I also triangulated methods, referring to the published literature, as described above.
Model inputs included epidemiological and cost data from the six hospitals, focus group discussions and published sources as described above.
For fluorescent labeling of the S6C mutant, we applied minor modifications to a published protocol as described.
These patients were compiled from five previously published studies, as described in Table 1 (Validation Series A).
CCHFV small fragment RNA was detected with SuperScript III Platinum SYBR Green One-Step qRT-PCR (Invitrogen, Carlsbad, CA, USA) and published primers as described (5 ).
A log2 ratio cut-off of +/− 0.8 was used to stringently define gene amplification and deletion, respectively, based on prior published studies as described in the methods section [ 7, 18, 19].
An article describing an instrument to measure impairment resulting from ED psychopathology has also been recently published, but, as described, neither the important conceptual distinctions between impairment and quality of life; nor the complexity of causal pathways between symptoms and behavioural manifestation in the illness, are recognized [ 25].
