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These data are well-organized and accessible through the Saccharomyces Genome Database (SGD) [2], a public database that curates the yeast genes and also compiles Gene Ontology (GO) annotations, publications, interactions, and a multitude of additional information.
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The 'interaction objects field' also retains the original relationship information in fields such as publication, interaction type and detection method allowing, for example, the separate scoring of all the individual pieces of evidence for a particular binary interaction, which can then be resolved into a single cumulative score.
The MetaCore interactive database has been manually curated from publications describing interactions among proteins and small molecules of biological relevance in humans.
Although a number of previous publications showed interactions between a group of residues on the CID and the enzyme substrate and reported the possible functional significance of the CID [14], [20], [32], [34], [38], the definitive role of the CID in chitinase function has not been completely determined [17], [24], [32].
This was deemed necessary as two publications per interaction can limit inclusion of potentially interesting interactions included in other pathway resources (KEGG, Reactome etc) and newly discovered interactions.
This gap has been filled by the publication of Interactions (Roast Books), a collection of short pieces by some distinguished writers with experience of stroke, headed by Seamus Heaney and Alan Ayckbourncorrect.
Figure 4a illustrates the difficulty of curating a publication describing interactions between a well-known breast cancer protein BRCA1 and another protein, BAP1, which binds to BRCA1 and enhances cell-growth suppression (43).
In order to evaluate the resilience ability of first-year students of Spanish architecture degree, we have compared two learning methodologies: the traditional generation of printed plans, and the generation of interactive 3D models using new systems of publication and interaction.
Both the social and the community teams will form part of the Guardian's editorial audience team, led by Mary Hamilton, which manages all aspects of the publication's interaction with its audiences, incorporating moderation, reach and optimisation, as well as social media and community journalism.
Complementarily, one of the Dutch food companies expressed that differing interests (e.g. business profit and academic publications) can ease interactions among stakeholders (Blok et al., 2015).
The number of publications addressing gene environment interactions reflects a robust interest toward gaining much needed knowledge in the area of metabolic traits and cardiovascular diseases.
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