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Arena said its drug, called lorcaserin, which works by a different mechanism, did not show psychiatric side effects.
Makers of the two most common drugs used to treat and prevent flu should add warnings that they may cause psychiatric side effects, federal regulators have recommended.
Last year, the agency added a requirement that all patients acknowledge in writing that they are aware of the possible psychiatric side effects.
Food and Drug Administration warnings on packaging also note "high potential for abuse," as well as psychiatric side effects such as aggression, hallucinations and paranoia.
In the clinical trials that led to its approval, Stribild was roughly equivalent to Atripla and to another combination, though it avoids some psychiatric side effects of Atripla.
Twelve patients at Sewri, Mumbai's only TB hospital, have committed suicide in the past three years, with the psychiatric side effects of TB drugs suspected of playing a part.
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However, there have been only three case reports of patients with bipolar disorder (BD) who experienced an untoward psychiatric side effect while receiving isotretinoin treatment.
Terizidone was substituted if there was a serious psychiatric side effect.
As a result of the psychiatric side effect profile, the US Food and Drug Administration declined permission for rimonabant, and in October 2008, rimonabant was also suspended across the EU.
Eleven of 12 subjects (92 %) reported at least one AE during DTG + EFV dosing; the most frequently reported AEs were dizziness [11 subjects (92 %)] and abnormal dreams [5 subjects (42 %)], which were considered by the investigator to be related to EFV based on its known psychiatric side effect profile.
Concerns over the health of British soldiers given an anti-malarial drug which can induce psychotic behaviour and other psychiatric side-effects have prompted the Commons Defence Select Committee to hold an inquiry into the Ministry of Defence's use of Lariam.
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