Sentence examples for psychiatric relevance from inspiring English sources

Finally, we examine the psychiatric relevance of making affectively charged inferences, especially about the self.

Whereas zebrafish do not generally phenocopy human behaviour, they do exhibit a repertoire of stereotypic behaviours with potential psychiatric relevance that could be useful indicators of gene function (Brennan, 2011; Stewart et al., 2013).

A major psychiatric relevance of NRG1 emerges because its locus is implicated in neurodevelopmental disorders (Tabares-Seisdedos and Rubenstein 2009) and, in particular, from evidence that NRG1 is a schizophrenia susceptibility gene, in its own right (Stefansson et al. 2002; Li et al. 2006; Keri et al. 2009) and in epistasis with other genes in the NRG1 signaling pathway (Nicodemus et al. 2010).

Furthermore, administration of the aqueous extract might offer a useful alternative or complementary choice in either the prevention or the treatment of psychiatric condition with relevance for PD.

Individual candidate genes can be evaluated with these quality parameters in post hoc analysis to help strengthen the relevance to psychiatric disorders.

The resulting liability index can be used as the core phenotype for subsequent analyses searching for specific causal genes and functional genetic variants of relevance to psychiatric disease.

In recent years, epigenetic factors have become an avenue of investigation with some promise (Labrie et al. 2012), with the complex epigenetic regulation of Bdnf showing relevance to psychiatric disorders and environment (Boulle et al. 2012).

A knockin mouse model of a common polymorphism in the brain-derived neurotrophic factor gene (BDNF) provides examples of how such a vertically integrated translational approach can identify robust genotype-phenotype relationships that have relevance to psychiatric practice.

The default-mode network (DMN) is a functional network with increasing relevance for psychiatric research, characterized by increased activation at rest and decreased activation during task performance.

Importantly, this is an area of research with potential clinical relevance for psychiatric conditions characterized by excessive rumination [54], such as obsessive-compulsive disorder [55], anxiety disorder [56], and major depression [57], [58], [59].

Acute risperidone, olanzapine, and clozapine treatment increases inhibitory GSK3β phosphorylation in multiple brain regions of relevance to psychiatric disorders.