Your English writing platform
Discover LudwigExact(8)
The third site, designated as pseudo site 3, constitutes a large interface between Wnt3a and a second CRD.
We also show that BC hybrids can function efficiently in HeLa cells, in both extra-chromosomal and pseudo site assays.
Mutations in pseudo site 3 either abolished or enhanced Wnt3a signaling, suggesting a dual role in signal modulation.
In line with its parental enzymes, we found that BC{−1} integrase was able to carry out pseudo site integration in HeLa (Fig. 6D).
Recognition of both pseudo site types may preclude usage of BC{−1} for genomic engineering due to safety concerns, as recombination between said sites could lead to unwanted inversions, deletions and/or translocations.
Janda et al. have in addition reported a third contact site in the crystal structure designated as pseudo site 3, which was speculated to mediate asymmetric Wnt/Fz dimerization and thus self-assembly to polymers.
Similar(52)
Thus, these sites were classified as pseudo sites (as Pseudo. in Figure 1B).
The procedure of linear discriminant analysis is to find a linear combination (the linear discriminant function, LDF) of these characteristics, that provides maximum discrimination between real and pseudo sites.
phiC31 integrase has also been used for integration into endogenous "pseudo sites" in certain cellular environments, however it does not appear to be universally capable of this reaction (Chalberg et al., 2006; Groth et al., 2004; Ma et al., 2006; Ni et al., 2012; Olivares et al., 2002).
MySpace TV will launch on Thursday and with YouTube's U.S. viewers only slightly outnumbering those of MySpace's current video pseudo-site, it looks like it will be a strong competitor.
To detect site specific integration at mpsL1 (mice pseudo-site from liver ), a nested PCR approach was followed.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com