For the pEM data, these components fell into two distributions: a relatively concentrated, high-amplitude distribution with a peak at 1144±1 ps and a second broad, low-amplitude distribution with a peak at 3044±17 ps (peak ± fitting error) (Fig. 4A).
The observed nonlinearity was dominated by a two-step decay, having a fast initial component with a time constant of around 1 ps and a second slower decay of around 50 ps (the biexponential fit is given in Figure 3c (red curve) upper panel together with the 1500 nm decay in black).
To this end, a combination function is defined, which is a function of a first stage p-value p and a second stage p-value q, where the latter is computed from the second stage data only.
The plasmid pL0018 contains two expression cassettes, one for the expression of the selectable marker Toxoplasma gondii dhfr (tgdhfr) under the control of the P. berghei dhfr promoter (dhfr p) and a second under the control of the P. berghei ef1α p that allows constitutive expression of any inserted downstream transgene.
To test for differences in breeding success between mating treatments, we fitted two versions of the likelihood in eq. (1): one in which breeding success differed between mating treatments (i.e., ps and pm were estimated as distinct parameters (ps ≠ p m ), and a second in which the multiply and singly mated females had the same probability of success (p s = p m = p).
In this study, we focused on the main breeds: Breton (B), Comtois (C), Percheron (P) and a fourth category designated Ardennais (A) including Ardennais, Auxois, Trait du Nord breeds between which the genetic distance is very small and that can mate together (Leroy et al., 2009).
The significance level was set to 0.01 for Bonferroni-adjusted p-values, and a second threshold for a trend towards statistical significance was set at 0.05 for unadjusted p-values.
AAA proteins form ATPase active sites at clefts between two subdomains: one containing a series of parallel β-strands (P loop) and a second called the lid.
It has been reported that ThiD is able to phosphorylate HMP to HMP-P and in a second step HMP-P to HMP-PP [7], [17].
The CDC classified twice as many children as obese compared to the IOTF 16.6% versus 8.3% (p <.001) and a third more than the WHO 16.6% versus 11.3% (p <.01).
The most significant transcript showing an interaction effect was Pitx2 (Illumina probe 1820746, P = 0.0007) and a second Pitx2 probe ranked 7th (Illumina probe 7320338, P = 0.002).
