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Co-segregation of the respective phenotype with specific chromosomal markers is used to determine a chromosomal region in the proximity of the underlying disease gene.
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The OSE envelopes the ovary and is therefore in close proximity to the underlying stromal, granulosa and thecal cells.
In this study, we assessed the prevalence of ID in a large unselected population of patients with different types of solid and hematological malignancies and evaluated interdependencies between ID and stage, disease status, proximity of treatment of the underlying cancer, as well as possible correlations with performance status.
We examined 3,110 vertebrate-specific and ~82,000 mammalian-specific CNEs across 19 and 9 mammalian orders respectively, and tested for changes in the rate of evolution of CNEs located in the proximity of genes underlying the development or functioning of auditory systems.
This demonstrates that the initial direction of catalyzed nucleosome translocation is determined by the underlying 601 DNA sequence rather than the length of the two flanking DNA arms, ruling out DNA-end proximity effects as the underlying cause of this observation.
Because of the close proximity of PAT to the underlying myocardium, it has been hypothesized that PAT may have a local deleterious effect on cardiac structure and function (2– 4).
Treatment is of the underlying disorder.
Again, treatment is of the underlying disorder.
Their value depends on the price of the underlying stock.
Monitor the color of the underlying skin.
Depending on the physical proximity of genes underlying QTL, they may or may not co-segregate.
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CEO of Professional Science Editing for Scientists @ prosciediting.com