Sentence examples for proximity gene from inspiring English sources

It is now appreciated that recombination events at antigen receptor loci depend on locus conformational changes that bring into proximity gene segments that may be widely separated in the linear DNA sequence.

However, for lyrata, with diploids and polyploids in close proximity, gene flow seems to be bidirectional.

Finally, we measured the extent to which co-evolutionary relations coincide with other cellular relations such as genomic proximity, gene fusion propensity, co-expression, protein protein interactions and metabolic connections.

Available information about each of the listed genes – for example, about SNP proximity, gene expression, expression quantitative trait loci (eQTL; see below), known animal models and the phenotype of interest – can then be collated, and the plausibility of each gene as a candidate involved in disease can be evaluated.

The Predictome database is based on the implementation of published computational methods and publicly available data and can precisely predict the connections between proteins; the associations are created using a variety of techniques, both experimental (yeast two-hybrid, immuno-coprecipitation, correlated expression) and computational (gene fusion, chromosomal proximity, gene co-evolution).

We first used a method proposed in William and Bowles [ 15] to examine the degree of coexpression among proximity genes.

If the average copy number was less than two across all five genomes then we also considered the proximity of genes in inferring gene modules.

Additionally, EAC and UPSC tpDMRs were enriched in proximity to genes with different gene ontology terms (Additional file 2: Figure S3A).

These methods provide a low-dimensional point representation of genes, where the proximity of gene-specific points indicates a similar codon usage of the associated genes.

Mani, R. S. et al. Induced chromosomal proximity and gene fusions in prostate cancer.

Spatial proximity between gene pairs whose midpoints fall in to the same 1 Mb grid were assigned a missing value.