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The sparse network of basin monitoring in the study area does not favor the spatial proximity approach, producing the worst regionalization solution.
The results from both models show that the spatial proximity approach marginally outperforms the physical similarity approach and both approaches are better than random selection of a donor catchment.
We present a photoaffinity labeling study of the human Angiotensin II (AngII) type 1 receptor (hAT1) and a constitutively active mutant (CAM) N111G hat1 at multiple temperatures using a p-benzoyl-l-phenylalanine (Bpa) containing AngII analogue 125I-[Sar1 125I-[Sar1II and the Methionine Proximity Approach (MPA).
The proximity approach is widely used in many influential environmental epidemiology studies [ 10, 11, 25– 29].
Within the two latency and frequency variables, these four parameters (proximity, approach, touch, manipulation) were highly correlated, using the intra-class correlation coefficient (above 0.7, p < 0.05) to test for consistency between parameters.
The proximity approach has been utilized frequently in many influential epidemiological and public health studies, particularly in the assessment of health effects around petrochemical industrial complexes [ 10, 11] and heavy metal smelters [ 32, 39].
Similar(52)
However, this can largely be overcome by using proximity approaches, such as bioluminescence resonance energy transfer (BRET), which localise the signal (within 10 nm) to the specific receptor target.
To validate the proximity approach-based exposure classification, we constructed monthly wind roses of the area for the entire study period.
Similarly, Willner and co-workers incorporated a DNAzyme system into HCR but also utilized proximity approaches by splitting the DNAzyme into two subunits that would only efficiently reassemble upon input strand-mediated concatemer formation.
During this time, the number of inspections ('frequency'), proximity of approach during each inspection ('mean distance') and group size at approach (to calculate '% alone') were all recorded.
This technique, however, lacks specificity; so another proximity labeling approach was adopted.
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