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In the Old World deer the second and fifth hand bones (metapodia) have almost completely disappeared except for proximal, terminal remnants.
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This site is located on the E-helix of the large lobe and interacts with the proximal end of the C-terminal tail.
These three helices form an elongated bundle with a ∼50° kink towards the membrane proximal C-terminal end.
The calculated structural model possesses a helical basic structure with two domains (proximal N-terminal, distal C-terminal domains), that enclose the central cofactor heme.
The identification of proximal N-terminal and C-terminal peptides indicated that the PEG11 protein was likely to be full length or near full length in sequence, as predicted from its size upon immunoblotting.
Most of the common proximal and terminal spacer alleles were only found within a single MLST clonal complex, except for ST-45 and ST-283 sharing proximal spacer allele 14, ST-48 and ST-257 sharing proximal spacer allele 22, whereas ST-21 and ST-61 share proximal allele 172 and terminal allele 289, and ST-354 and ST-443 share proximal allele 703 and terminal allele 799 (table 3).
To assess whether spacer diversity is linked with other sequence diversity in C. jejuni and C. coli, we first looked at the distribution of proximal and terminal spacer per MLST-clonal complex (table 3).
Chemical crosslinking mass spectrometry and small-angle X-ray scattering measurements localize CaM near the N-lobe of the TR kinase domain and the spatially proximal C-terminal helical repeat.
In order to increase the solubility of Dsp-CA-c, its proximal N-terminal amino acids 1 11 were substituted with VSEPHDYNYEK (NT11) of the N-half domain (Dsp-CA-n) which exhibits a high soluble expression yield.
It suggests that precisely timed spike patterns may be preferentially communicated via proximal synaptic terminals and between neurons with small membrane time constants.
The AT1 receptor was reported to traffic to cell nuclei by the presence of an NLS sequence in its 8th helix (membrane proximal C-terminal sequences) [41].
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