Sentence examples for proximal target from inspiring English sources

We scanned 3′ UTR SNPs with a potential functional effect on miRNA binding for cis-acting expression quantitative trait loci (eQTLs) for the corresponding proximal target genes.

Furthermore, the proximal target of cucurbitacin I relevant to cell migration is unlikely to be the same one involved in activation of the JAK2/STAT3 pathway.

Figure 5A shows that pyrvinium significantly down-regulates the induction of sXBP-1 mRNA by glucose deprivation, suggesting that XBP-1 is the more proximal target of pyrvinium than GRP78.

This was expected, because the UFOV test was the proximal target outcome for the speed of processing intervention.

To investigate the effect of the loss of DOT1 on Mec1 kinase activity directly, we analysed the phosphorylation of its proximal target Ddc2, after DNA damage.

We have previously reported that proximal target inhibition is necessary but not sufficient to achieve antitumor effect (Jimeno et al, 2005, 2006).

For example, some specific jet nebulizers may deliver large particles (>5 µm for proximal targeting), whereas others deliver nanoparticles.

However, IL-22 protein is often undetectable in serum from healthy individuals and not systematically detectable in CD patients, making this proximal target-engagement biomarker hard to use as an index of disease clinically.

These outcomes are often defined as the proximal targets of intervention approaches from a developmental perspective.

The proximal targeting arm (2.1 kb) was amplified (oligos oMT1-2, Mengyao Tan, University of Utah, Salt Lake City, UT) and cloned into the [2 3] donor.

Proximal targets in the brain receive direct projections from both SCN shell and core neurons, with tissue-specific differences in the density of innervation from each region [ 5].