Sentence examples for proximal pair of from inspiring English sources

Conversely, a multimerized 236-bp fragment, pHS1, containing the proximal pair of GAGA sites has enhancer blocking activity during early embryogenesis, but not thereafter.

Other things being equal, a CR domain possessing the central aspartate should engage a proximal pair of positive charges with ~7 kJ/mol more binding energy than one lacking the aspartate residue.

This grouping was supported by a combination of homoplasious characters such as characters of antennal scaling and the tendency to have the proximal pair of tibial spurs of the hindleg on the proximal half of the leg.

Our findings establish a preponderant contribution to ligand binding from engagement of a CR domain that contains a DxDxD or DxDDD motif with a ligand that has a proximal pair of positive charges, though these charges may be contributed by lysine, arginine or even protonated histidine side chains.

The low binding affinity seems surprising given that LB3 and LB4 are the two LDLR domains that each contains the DxDxD motif and the D3 domain of RAP contains two critical lysine residues (Lys and Lys) that have been implicated in binding to LRP [ 32], each of which occurs as a part of a proximal pair of lysine residues (Lys with Lys and Lys with Lys).

This is consistent with the existence of localized clusters, but does not distinguish between tightly packed co-expressed clusters or dispersed proximal pairs of co-expressed genes.

In oPOSSUM-2, an additional analysis method called Combination Site Analysis (CSA) was introduced to identify over-represented proximal pairs of TFBSs.

Under this assumption, we illustrate that closely positioned sites tend to be activated by the same kinase (86% of proximal pairs of phosphosites, compared to 62% of non-proximal pairs).

As the number of proximal pairs in LD is O(m), the cost of this correction is minor.

The specific reciprocal coupling pairs included both distant pairs and proximal pairs.

The unique FRT-like sequences were classified based on the number of matches to FRT within the first four proximal bases pairs of the Flp binding elements of FRT and the nature of mismatched base pairs in the same region.