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Cisplatin and gemcitabine are chemotherapeutic agents which are also known for provoking alteration in the expression levels of Bcl-2 proteins [ 28, 29].
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The global environmental damage caused mainly by anthropogenic activities such as fossil fuels and the emission of greenhouse gases (GHG) to the atmosphere has become more severe in recent years, provoking alterations such as the so-called climate change and its consequences.
The catalytic activity of the allosteric enzymes is modulated through the noncovalent binding of a specific metabolite at a place of the protein different from the catalytic site, provoking alterations of the metabolic state in an interval of seconds.
In particular, neoplastic growth induces important modifications, not only of the DNA, but also of the composition and distribution of the histone and non-histone nuclear proteins, thus provoking alterations of the distribution of heterochromatin in the nucleus.
It has been shown that experimental induction of high IOP levels provokes alteration of the autoantibody pattern [ 26].
While the beanballs fired by baseball pitchers often provoke altercations, Williams's relentless body shots yielded little more than a shrug from Soler-Espinosa and Suárez Navarro.
Thus, FLG deficiency provokes alterations in keratinocyte architecture that influence epidermal functions localizing to the extracellular matrix.
Modifications in vital cellular molecules can provoke alterations in the cellular structure causing malfunctions that may finally result in apoptosis or necrosis.
The intent of this study is to examine whether intrauterine malnutrition provokes alterations in the progression of the acute and subchronic inflammatory response, and its influence on the pharmacological effect of indomethacin.
The results of the present study suggest that food restriction in rats provoked alterations in erythrocyte parameters in mothers, probably as a consequence of disturbance in the iron status.
It has been shown that most patients with a history of unstable ACJ injuries managed conservatively develop changes in the anatomical orientation of the scapula, which provokes alterations in the dynamics of the rotator cuff, which can eventually predispose chronic pain [2].
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