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It forms pores in the cell and mitochondrial membrane of neutrophils and macrophages and thus provokes cell lysis and apoptosis with subsequent liberation of inflammatory mediators [4, 7].
However, if degradation of Pfkfb3 is inhibited, glycolysis is stimulated and oxidative stress results [56]; in neurones this provokes cell death [57].
A single type of mechanical stimuli in vitro often provokes cell's sensing and responding to external forces via multiple molecular events (Fig. 1A).
We show that H-RasV12 provokes cell cycle arrest accompanied by accumulation of p53 and p16INK4a in immortalized FHL2−/− MEFs.
Thereafter, autophagy is predominantly activated in the cytoplasm where it provokes cell death.
It forms pores in the cell and mitochondrial membrane of neutrophils and macrophages and thus provokes cell lysis and apoptosis with subsequent liberation of inflammatory mediators [ 4, 7].
Similar(53)
Long-term activation of Hog1 leads to a sustained cell-cycle arrest that, when maintained, provokes cells to enter into apoptosis (Vendrell et al. 2011).
We selected a C-60 suspension that has previously been shown to provoke cell membrane destabilisation in vivo.
In the intrinsic pathway (route 2), diverse stimuli that provoke cell stress or damage typically activate one or more members of the BH3-only protein family.
Here we demonstrated that CRISPR-Cas9 system can effectively trigger programmable double strand break (DSB) at the chromosome of PCC 7942 and provoke cell death.
As expected, the ingestion of concentrated sera provoked cell death.
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CEO of Professional Science Editing for Scientists @ prosciediting.com