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Given that the structural integrity of EDIII is essential for its immunogenicity, the gene-based vaccines (this study), which eliminate this variability are far more desirable, with the added advantage that these can also provoke potent CMI.
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The relative contribution of these factors is unclear but it is known that swelling alone provokes potent quadriceps AMI.
In vitro and in vivo experiments have demonstrated that some CT antigens, for example, NY-ESO-1, are capable of provoking potent T-cell-mediated immunity to directly kill tumour cells and/or release cytokines to interfere with the growth and propagation of tumour cells (Jager et al, 2001; Kirkin et al, 2002).
The knowledge of how and in combination with which additional chemotherapeutics Bcl-2-antagonizing protocols provoke a potent anticancer effect will strongly foster the clinical evaluation of Bcl-2-targeting strategies.
In this regard, PV-3Cpro provoked a potent inhibition of ongoing protein synthesis by PABP hydrolysis.
It was hypothesised that facial stimulation would provoke the most potent vascular changes.
The shooting, on Sept. 16, and the deaths of two Iraqi women in a shooting by a different security company on Tuesday, have provoked anger at politically potent levels of Iraqi society.
In migraineurs pituitary adenylate cyclase activating peptide1 38 (PACAP1–38) is a potent migraine provoking substance and the accompanying long lasting flushing suggests degranulation of mast cells.
The potent headache provoking property of PACAP1 38 [10] in comparison with the poor effect of VIP [11], suggests PAC1- R to be an interesting target for migraine treatment.
Glyceryl trinitrate (GTN) is a potent migraine provoking substance that in low doses causes degranulation of dural mast cells after i.v. infusion to awake as well as anaesthetized rats [80, 81].
The mice developed early and aggressive T cell neoplasias with features of immature thymocytes, including expression of the pT α, a defining component of the pre-T cell receptor, known to be a potent signaling complex provoking thymocyte survival, proliferation, and activation.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com