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Four AS bronchial provocation challenges were carried out at 1 week intervals, followed by one of four treatment protocols: SAL, IB, SAL/IB or control (untreated).
36 Such cross-sensitivity can be identified from clinical history, in vitro quantification of allergen-specific IgE, skin test reactivity and provocation challenges with purified allergens.
Reliable methods of diagnosing ASA sensitivity have been developed and provocation challenges can be done via oral, intranasal, inhaled, and i.v. routes.
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Her words carried the ring of deliberate provocation, challenging the Islamists to put a fatwa on her and raise a sword to behead her.
EAHR can be assessed during inhalational provocation challenge.
Hypertonic (4.5%) saline provocation challenge identified EAHR with attenuation of the inspiratory flow curve.
Visit 3 included a fibreoptic laryngoscopy, followed by hypertonic saline provocation challenge (HSC) with inspiratory flow volume curve measurement [ 20, 21] and then post-challenge laryngoscopy.
Laryngoscopy was repeated before and after hypertonic saline provocation challenge at visit 5. Inspiratory/expiratory flow volume curves were performed before and during saline challenge, after each dose.
Provocation challenge tests such as EVH and the MCT have therefore been used to assess exercise-induced bronchoconstriction and asthma in athletes in a standardized fashion.
One solution to these potential problems could be a bronchial provocation challenge that would reproduce the hyperventilation of exercise, e.g. eucapnic voluntary hyperventilation of cold and dry air [ 20].
We have developed a one-week inpatient 'running re-education' programme where patients with BOS undergo initial assessment with the Provocation Challenge Test (PCT) and assessment of two-dimensional (2D) running kinematics.
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