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Provision of adherence data to providers may motivate patients to improve adherence and help providers identify adherence barriers.
The provision of adherence support by families, HEWs and community volunteers was also suggested to strengthen service delivery.
The median (IQR) intervention exposure was 175 (118–263) min. The comparison group was 'standard care' for all studies; for 13 studies (50%), standard care involved some form of technique to improve adherence such as education, encouragement or provision of adherence aids and in these studies, recipients of the intervention received further techniques such as MI.
Review of the 14 remaining trials revealed that all interventions aimed to improve medication management skills; this involved various techniques, for example, adaptation of dose schedules according to participants' risk factors and/or provision of adherence gadgets such as timers [ 30- 43].
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Four studies did not have an intervention in which a pharmacist was actively involved in the provision of adherence-enhancing strategies for oral type 2 diabetes mellitus medication.
The provision of specific adherence support is associated with enhanced adherence of initially non-adherent patients.
The provision of specific adherence support is associated with enhanced adherence of initially non-adherent patients, whereas initially adherent patients remain adherent for at least six cycles without specific support.
Feedback of infection rates may have promoted more reliable provision of and adherence to the well known technical aspects of infection prevention for CVCs.
The trial's Adherence Support Program (ASP) employs "job aids" (flip charts, information leaflets, and clock/calendar materials) and carefully constructed messages to support the provision of personalized adherence counseling to trial participants [ 33].
In addition to the review by MSF listed above, other practitioners examined the implementation of programs for provision of ART, adherence to ART and the challenges therein among conflict-affected populations in Kenya and Republic of Congo [ 18, 24- 26].
However, this study will provide the economic costs associated with the provision of an adherence intervention led by specialist nurses and allied health professionals working within the local hospital and costs will be based upon local sources to provide a more realistic consideration of associated costs.
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