Exact(13)
But more than a third of the 90 drugs approved under the program since 1992 never had studies done proving efficacy.
However, empirical evidence shows that although double-blind randomized controlled trials are the gold standard for proving efficacy of a therapeutic procedure, they often suffer from lack of generalizability [26].
Now, because of concerns for proving efficacy amid declining cases, Lane said NIAID is exploring options to bring the vaccine trials to hot zones.
"We're at this different stage of the outbreak," Schwartz, the bioethicist, explained, saying there is now a problem in that having so few cases makes it extremely difficult to clinically test the vaccines in the face of the epidemic, a crucial aspect of proving efficacy.
Cure rates were also stratified by country and age (age groups: ≤12 months; >12 months), though the study was not powered for proving efficacy within each country or age group.
In surgical research where there is no suitable comparator, proving efficacy may require the use of placebos.
Similar(47)
Under the new proposals, drug companies will do what trials they can in infected people, but can run more safety tests in healthy people, and prove efficacy through tests on bugs in laboratories.
Sorafenib has proven efficacy in metastatic renal cell carcinoma (mRCC).
The first-generation (nicardipine) agents have proven efficacy against hypertension.
Moreover, a multicenter RCT would be feasible and would require 280 patients to prove efficacy.
Citicoline is the only neuroprotectant that has proved efficacy in patients with moderate to severe stroke.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com