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Local healthcare provider organisations (PCTs and successor organisations) reported that they had to find funding to order the vitamins, record how many were distributed to eligible women and children and then claim reimbursement from the Department of Health, providing proof of use in the form of the vitamin coupons.
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Candidates need to not only showcase their skills but provide proof of using those skills.
Here, we explore this approach by analyzing the composition of the bacterial SOS regulon in the human gut microbiome through in silico and in vitro analyses, providing proof-of-concept for the use of metagenomic data in the inference of regulatory meta-networks.
Two inspiring studies showed that three-dimensional intestine and liver can be derived from iPSCs [26,27], providing proof-of-concept that iPSCs can be used to generate functional organs in vitro for regenerative medicine.
This article is part II of a two-part series providing proof-of-concept for the diagnostic and therapeutic use of the DAB4 clone of the La-specific monoclonal antibody, APOMAB®.
In summary, our results show that humans and pigs share similar genetic architecture for complex traits, providing proof of concept for using swine as a model organism for complex human diseases.
Nevertheless, a new MC4R agonist, RM-493 (previously BIM-22493), was recently shown to decrease adiposity, increase energy expenditure and improve glucose metabolism with no detrimental cardiovascular effects in DIO rhesus macaques (Kievit et al, 2013), providing proof of concept for the use of MC4R-agonists to safely treat the metabolic syndrome.
Never make withdrawals on retirement accounts without providing proof of their acceptable penalty-free use.
The fast forward genetics approach is highly efficient compared to traditional approaches and while we provide proof-of-principle using Arabidopsis thaliana it can in principle be applied to any sequenced species of interest and is largely independent of the genome size.
Here, we provide proof-of-concept for using multimodal magnetic resonance imaging (MRI) as a diagnostic biomarker for ALS.
The platform is scalable to microwell formats, and we provide proof-of-concept for its use in testing entry inhibitors and antiviral compounds.The lack of models that mimic hepatitis B virus (HBV) infection in a physiologically relevant context has hampered drug development.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com