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It has been proposed that CD30 provides proliferation and/or survival signals during lymphocyte responses (Croft, 2003).
EGF provides proliferation, differentiation and survival signals and the membrane-bound EGF receptor is associated with several types of cancer if its expression or activation changes erroneously.
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Furthermore, acellular-derived matrices serve to stimulate proliferation and recruitment of endothelial cells by providing proliferation signals to cells.
Multinational energy complex with a closed fuel cycle facilities should provide proliferation resistance with an institutional barrier.
A combination of 5 µg/ml soluble anti-CD3 (clone HIT3a) and 2.5 µg/ml soluble anti-CD28 (clone CD28.2; eBioscience,) provided proliferation stimulus for a 120 h culture period.
Before puberty, immature Sertoli cells provide proliferation and differentiation signals for Spga.
Both E2 and IGF-I synergistically provide proliferation signals to breast cancer cells, but E2 is essential for the proliferation of MCF7 cells [ 45].
It is possible that the very initial genetic alterations in tumorigenesis, presumably the ones that provide proliferation advantage, may also enable cell dissemination.
Because the canonical function of telomerase is to lengthen telomeres, and long telomeres provide proliferation potential, we conducted telomapping assays to determine whether telomerase hyperactivation leads to changes in telomere length during heart regeneration (Flores et al., 2008).
In fact, this niche environment has been associated with regulating key stem cell functions, such as maintaining stem cell quiescence and providing proliferation- or maturation-inducing signals when numerous progenitor cells are required to generate mature cell lineages.
It has been shown that RP105 can provide proliferation and activation signals in B cells [ 28] and that B cells from RP105-deficient mice were hyporesponsive to TLR4 and TLR2 stimulation [ 30, 31].
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