Importantly, this OHT treatment of Neurog2ERT2- and Ascl1ERT2-transduced astroglia triggered similar reprogramming efficiency (40% of DsRed+ cells), thus providing a suitable system for the investigation of the transcriptional changes during reprogramming triggered by the two factors.
Overall, the protein expression system used here facilitates the generation of milligram amounts of purified protein that is enzymatically active and appears to be structurally stable, provided it is stored at high concentrations (> 10 μM) and thus provides a suitable system to generate sufficient protein for future drug-screening efforts.
Identifying genomic phenotype and corresponding functional changes in hyperglycemic endothelial dysfunction will provide a suitable systems biology approach for understanding underlying mechanisms and possible effective therapeutic intervention.
This tool provides a general assessment of available technologies and systems for assisting researchers to select a suitable system for their ChIP-Seq analysis.
Apoptosis is a suitable system for mathematical modeling.
Thus, Legionella provides a suitable genetic system for future characterization of Rvh scaffold components, as well as for testing the translocation of predicted effector molecules.
The coexistence of these species provides a suitable model system for the investigation of factors shaping the distribution of closely related, cryptic species.
Since R. pirica possesses both inducibility and reversibility of the bulgy morph phenotype, it provides a suitable model system for experimental analysis of the genetic basis and mechanism of morphogenetic changes.
Thus, EC provides a suitable model system to study local adaptations.
In summary, data presented here demonstrate that TGF-β3-bound hyaluronan microspheres provide a suitable delivery system for induction of hMSC chondrogenesis and their use may represent a clinically feasible tissue engineering approach for the treatment of articular cartilage defects.
