Sentence examples for provides a structural framework for from inspiring English sources

This study provides a structural framework for how a Swi2/Snf2 ATPase interacts with its substrate DNA:protein complex.

Our computational approach provides a structural framework for chemical biologists to characterize kinases in the inactive state and to explore new chemical spaces with structure-based drug design.

According to Cohen et al. [ 46], collagen is a principal component of connective tissue and provides a structural framework for the regenerating tissue.

Taken together, the newly defined modular organization of the core Mediator provides a structural framework for understanding the function of Mediator in PIC assembly.

The architecture of Bacillus AddAB also provides a structural framework for the enigmatic AdnAB helicase nucleases that are restricted to the actinomycete niche (Unciuleac and Shuman, 2010).

The cytoskeleton provides a structural framework for the cell, serving as a scaffold that determines the cell shape and the general organization of the cytoplasm [ 38].

The crystal structures of the ClC channels of Escherichia coli and Salmonella typhimurium provide a structural framework for the entire family.

The structures allow a detailed rationale to be developed for the observed affinity of the PU3 class of compounds for HSP90 and also provide a structural framework for design of compounds with improved binding affinity and drug-like properties.

These findings together with previously reported data on wt and mutant p53 provide a structural framework for understanding p53 dysfunction as a result of oncogenic mutations and its rescue by suppressor mutations and for a potential drug design aimed at restoring wt activity to aberrant p53 proteins.

The models provide a structural framework for interpretation of the resulting functional analysis.

Our models provide a structural framework for interpreting experimental data and allow predictions of the TLR signal transduction process.