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In summary, this work provides a mechanistic characterization of the role of the RNA helicase DHX34 in mRNP remodeling leading to activation of NMD.
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These results, providing a mechanistic characterization of the novel monofunctional platinum complex-induced cancer cell death, shed light on exploring a new tool to overcome apoptosis-resistance in patients with ovarian cancer.
The current work focuses on a mechanistic characterization of polyglutamine homodimerization as a function of chain length and temperature.
The computational model provides a mechanistic understanding of how different lineages arise from the dynamics of the underlying regulatory network.
This provides a mechanistic explanation of the regulatory effect of FE65 Ser phosphorylation on APP processing.
This result thus provides a mechanistic underpinning to the selectivity of OEE for MAO-A.
This work provides a mechanistic link between the stimuli of neuronal plasticity and postsynaptic potentiation.
This finding provides a mechanistic explanation for the pathogenic role of IL-6 in PC progression.
This provides a mechanistic basis for the observed morphogenetic role of formins.
A model of TOR-driven aging provides a mechanistic explanation.
The presence of a functional PTD in prion protein provides a mechanistic basis underlying infectious PrPSc transport between cells.
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