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The hydrophobic character of the ACC carrier provides a high affinity of CIC to non-aqueous phase liquids (NAPL).
It provides a high affinity at dopamine D2 receptors but acts in contrast to other atypical antipsychotics as a partial agonist.
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This observation agrees with a previous report that the artificial UACUAAC sequence serves as an optimal branch point sequence in mammals (Zhuang et al. 1989) and suggested that the Gomafu RNA provides a higher affinity binding site for SF1 compared to the intron branch point sequences of endogenous pre-mRNAs.
Our analysis indicates that its protein topology apparently evolved to provide a high affinity interaction site for FH/FHL-1 and leads to an atomic-level hypothesis for the functioning of BbCRASP-1.
Acinetobactin is synthesized from a 2,3-dihydroxybenzoic acid, threonine and hydroxyhistamine, and contains catecholate and hydroxamate groups that provide a high affinity for iron [ 25].
In addition, both the ACGT and GCN4 motifs in the ONAC024 promoter provides a high-affinity binding site for OsSMF1 compared to the ACGT motif in the ONAC026 promoter.
CNBD-A provides a high-affinity (slow disassociation) site for cGMP whereas CNBD-B has a lower-affinity (fast disassociation) site.
H3K9me3 provides a high-affinity-binding site for HP1 and promotes the imposition of the H4K20me3 mark by the Suv4-20h1 and Suv4-20HMTasesses (Bannister et al, 2001; Lachner et al, 2001; Nakayama et al, 2001; Schotta et al, 2004, 2008; Benetti et al, 2007b).
Taking into account the limitations of each of these techniques in analysing this complex association event, in summary we concluded that each trimer of UspA1 527 665) provides a high-affinity binding site for a maximum of two molecules of N-CEACAM1.
We decided to test if endogenous AR physically interacted with CXCR7-SBP in C7-SBP cells because the SBP epitope provided a high-affinity tag for the selective isolation of the CXCR7-SBP protein using streptavidin-affinity chromatography [ 42].
Protein translocation proceeds through one of the SecYEG complexes contained in the functional dimeric translocon, whereas the other copy helps to provide a high-affinity binding platform for SecA [ 9, 10].
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